Author: Marcotullio, Maria Carla; Pelosi, Azzurra; Curini, Massimo
Title: Hinokinin, an Emerging Bioactive Lignan Document date: 2014_9_17
ID: 04kh4yzy_33
Snippet: Medola and coworkers studied the mutagenic and/or antimutagenic effects of hinokinin (1) in vivo using the rat peripheral blood micronucleus test. The differences of micronucleated cells between treated animals and control were not significative, demonstrating no genotoxic effect, while co-exposition of the animals to hinokinin and DXR showed a significant reduction in the frequencies of MNPCEs (micronucleated polychromatic erythrocytes). However.....
Document: Medola and coworkers studied the mutagenic and/or antimutagenic effects of hinokinin (1) in vivo using the rat peripheral blood micronucleus test. The differences of micronucleated cells between treated animals and control were not significative, demonstrating no genotoxic effect, while co-exposition of the animals to hinokinin and DXR showed a significant reduction in the frequencies of MNPCEs (micronucleated polychromatic erythrocytes). However, this protective effect of hinokinin was not dose dependent [101] .
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