Author: Weishan Huang; Sabrina Solouki; Chavez Carter; Song-Guo Zheng; Avery August
Title: Beyond type 1 regulatory T cells: co-expression of LAG3 and CD49b in IL-10-producing T cell lineages Document date: 2018_6_30
ID: ivyp5cgz_26
Snippet: As discussed above, we demonstrated that co-expression of LAG3 and CD49b is a 259 generic feature of IL-10-producing T cells in vivo in the pulmonary tissues under multiple 260 inflammatory conditions (Figs. 2-3) . To determine whether this feature is applicable to IL-10-261 producing cells in other organs, we injected IL-10 GFP /Foxp3 RFP dual reporter mice with an anti-262 CD3ï¥ antibody that has been shown to stimulate pronounced IL-10 produc.....
Document: As discussed above, we demonstrated that co-expression of LAG3 and CD49b is a 259 generic feature of IL-10-producing T cells in vivo in the pulmonary tissues under multiple 260 inflammatory conditions (Figs. 2-3) . To determine whether this feature is applicable to IL-10-261 producing cells in other organs, we injected IL-10 GFP /Foxp3 RFP dual reporter mice with an anti-262 CD3ï¥ antibody that has been shown to stimulate pronounced IL-10 production by T cells through The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/359547 doi: bioRxiv preprint the IL-10-producing T cells following TCR activation in vivo, which again included Foxp3 + CD4 + , 266
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