Selected article for: "bp downstream and protein coding"
Author: Harlan Barker; Seppo Parkkila
Title: Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2
  • Document date: 2020_4_13
    • ID: 08vsaov7_12
    Snippet: Analysis of ACE2 promoter regions was performed using the TFBSfootprinter tool (https://github.com/thirtysix/TFBS_footprinting). Previous studies identified two distinct tissuespecific transcription start sites (TSS) for intestine and lung expression (36), which correspond to primary protein-coding Ensembl transcripts ENST00000252519 and ENST00000427411, respectively. These two transcripts were targeted for transcription factor binding site (TFBS.....
    Document: Analysis of ACE2 promoter regions was performed using the TFBSfootprinter tool (https://github.com/thirtysix/TFBS_footprinting). Previous studies identified two distinct tissuespecific transcription start sites (TSS) for intestine and lung expression (36), which correspond to primary protein-coding Ensembl transcripts ENST00000252519 and ENST00000427411, respectively. These two transcripts were targeted for transcription factor binding site (TFBS) analysis; input parameters of 1,000 base pairs (bp) upstream and 200 bp downstream, relative to the TSS.

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