Selected article for: "copy number and low level"
Author: Barker, Emily N.; Stranieri, Angelica; Helps, Chris R.; Porter, Emily L.; Davidson, Andrew D.; Day, Michael J.; Knowles, Toby; Kipar, Anja; Tasker, Séverine
Title: Limitations of using feline coronavirus spike protein gene mutations to diagnose feline infectious peritonitis
  • Document date: 2017_10_5
    • ID: 08b0g46x_50
    Snippet: Only one sample of abdominal fluid from a cat (#125) with severe interstitial pneumonia was found to be FCoV RT-qPCR-positive, at a low level (relative FCoV copy number 11.3; see Table 3 ); sequencing revealed mutated (nucleotide 23531A>C) FCoV. Cytological analysis of this sample was not performed. This cat also had a low relative FCoV copy number (4.7) in a sample of lung tissue, which had the same S gene mutation......
    Document: Only one sample of abdominal fluid from a cat (#125) with severe interstitial pneumonia was found to be FCoV RT-qPCR-positive, at a low level (relative FCoV copy number 11.3; see Table 3 ); sequencing revealed mutated (nucleotide 23531A>C) FCoV. Cytological analysis of this sample was not performed. This cat also had a low relative FCoV copy number (4.7) in a sample of lung tissue, which had the same S gene mutation.

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