Author: Chen, Qi; Wang, Leyi; Zheng, Ying; Zhang, Jianqiang; Guo, Baoqing; Yoon, Kyoung-Jin; Gauger, Phillip C.; Harmon, Karen M.; Main, Rodger G.; Li, Ganwu
Title: Metagenomic analysis of the RNA fraction of the fecal virome indicates high diversity in pigs infected by porcine endemic diarrhea virus in the United States Document date: 2018_5_25
ID: 1nyhllij_31
Snippet: In addition to obtaining mixed viral infection profiles of each sample, complete genome sequences of Aichivirus C and PSV were obtained and further characterized in this study. The clinical significance of PSV has not been confirmed to date, but this complete US PSV genome sequence can facilitate PSV diagnostics and future molecular epidemiological studies of PSV in US swine. It was also demonstrated in this study that there are at least two geno.....
Document: In addition to obtaining mixed viral infection profiles of each sample, complete genome sequences of Aichivirus C and PSV were obtained and further characterized in this study. The clinical significance of PSV has not been confirmed to date, but this complete US PSV genome sequence can facilitate PSV diagnostics and future molecular epidemiological studies of PSV in US swine. It was also demonstrated in this study that there are at least two genogroups of Aichivirus C (PKV-1) circulating in US swine. Currently, Aichivirus C-specific virological and serological diagnostic assays have not been available in most veterinary diagnostic laboratories. Availability of more Aichivirus C sequences will help understand genetic diversity of this virus and facilitate development of appropriate diagnostic assays. The clinical significance of Aichivirus C also remains to be elucidated.
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