Author: Paesen, Guido C.; Collet, Axelle; Sallamand, Corinne; Debart, Françoise; Vasseur, Jean-Jacques; Canard, Bruno; Decroly, Etienne; Grimes, Jonathan M.
Title: X-ray structure and activities of an essential Mononegavirales L-protein domain Document date: 2015_11_9
ID: 1taxqkk2_2
Snippet: In addition, however, paramyxovirus and filovirus L proteins contain a KxxxKxxG sequence (K-K-G motif) at their C termini, reminiscent of a signature motif for eukaryotic GTases, where one of the lysines forms the transient phosphoamide bond with Gp in the capping reaction 5 . A C-terminal domain of Rinderpest virus L (containing CR-VI and the downstream K-K-G motif) was shown to form such a bond 6 , leaving open the possibility that Paramyxoviri.....
Document: In addition, however, paramyxovirus and filovirus L proteins contain a KxxxKxxG sequence (K-K-G motif) at their C termini, reminiscent of a signature motif for eukaryotic GTases, where one of the lysines forms the transient phosphoamide bond with Gp in the capping reaction 5 . A C-terminal domain of Rinderpest virus L (containing CR-VI and the downstream K-K-G motif) was shown to form such a bond 6 , leaving open the possibility that Paramyxoviridae use GTase activity for capping.
Search related documents:
Co phrase search for related documents- Try single phrases listed below for: 1
Co phrase search for related documents, hyperlinks ordered by date