Author: Colino, Clara I.; Millán, Carmen Gutiérrez; Lanao, José M.
Title: Nanoparticles for Signaling in Biodiagnosis and Treatment of Infectious Diseases Document date: 2018_5_31
ID: 1bxwb2hj_133
Snippet: Depending on the type of regulation (i.e., whether quorum sensing induces or represses virulence), the agents will need to either inhibit or stimulate quorum-sensing-regulated gene expression. The latter is the case for the human pathogen Vibrio chlolerae, in which quorum sensing represses biofilm formation and virulence factor production [130, 168] . Many compounds have been described as inhibiting the bacterial communication process. Quorum sen.....
Document: Depending on the type of regulation (i.e., whether quorum sensing induces or represses virulence), the agents will need to either inhibit or stimulate quorum-sensing-regulated gene expression. The latter is the case for the human pathogen Vibrio chlolerae, in which quorum sensing represses biofilm formation and virulence factor production [130, 168] . Many compounds have been described as inhibiting the bacterial communication process. Quorum sensing interfering (QSI) agents can be either natural or synthetic compounds, as well as small molecules, enzymes and antibodies. Excellent and complete reviews of QS inhibitors have been published [130, 134, 149, 153, 155, 168, 170, 171] .
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