Author: Bohmwald, Karen; Gálvez, Nicolás M. S.; Ríos, Mariana; Kalergis, Alexis M.
Title: Neurologic Alterations Due to Respiratory Virus Infections Document date: 2018_10_26
ID: 0rlotyz3_40
Snippet: Despite HCoV capacities to infect CNS, it has been recently characterized, its presence in human CNS-related samples date back as early as 1980, where the first detection of this virus was performed in autopsy of patients with MS (Burks et al., 1980) . Following that, a few reports confirming the presence of this virus in samples from patients with MS was confirmed through several methods (Murray et al., 1992; Stewart et al., 1992) . The year 200.....
Document: Despite HCoV capacities to infect CNS, it has been recently characterized, its presence in human CNS-related samples date back as early as 1980, where the first detection of this virus was performed in autopsy of patients with MS (Burks et al., 1980) . Following that, a few reports confirming the presence of this virus in samples from patients with MS was confirmed through several methods (Murray et al., 1992; Stewart et al., 1992) . The year 2000, through research in an autopsy samples from patients with various neurological diseases (being MS most prevalent among them). showed that a 67% were positive for HCoV (with HCoV-229E being twice as common as HCoV-OC43; Arbour et al., 2000) . Moreover, the prevalence of OC43 in MS samples was statistically higher than in control patients, is the first report to provide a significant indication of the neurotropic capacity of these respiratory pathogens (Arbour et al., 2000) .
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