Author: Hsu, Shih-Hsien; Yeh, Ming-Lun; Wang, Shen-Nien
Title: New Insights in Recurrent HCV Infection after Liver Transplantation Document date: 2013_4_23
ID: 0hbeso65_17
Snippet: 2.6. Immunosuppression. Early data, examining the pathogenesis of graft injury in liver transplant recipients with HCV infection, first reported that methylprednisolone treatment for acute rejection led to a 4-100-fold increase in serum HCV RNA [31] . Since then, an aggravated course of HCV reinfection after LT and increased resistance to antiviral therapy have been attributed to the application of specific immunosuppressive medication [32, 33] ......
Document: 2.6. Immunosuppression. Early data, examining the pathogenesis of graft injury in liver transplant recipients with HCV infection, first reported that methylprednisolone treatment for acute rejection led to a 4-100-fold increase in serum HCV RNA [31] . Since then, an aggravated course of HCV reinfection after LT and increased resistance to antiviral therapy have been attributed to the application of specific immunosuppressive medication [32, 33] . Herein, various immunosuppression strategies have been evaluated for their influence on HCV recurrence.
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