Selected article for: "recent study and viral fusion"
Author: Hsu, Shih-Hsien; Yeh, Ming-Lun; Wang, Shen-Nien
Title: New Insights in Recurrent HCV Infection after Liver Transplantation
  • Document date: 2013_4_23
    • ID: 0hbeso65_38
    Snippet: Using a functional RNAi kinase screen, recent study identified epidermal growth factor receptor (EGFR) and ephrin receptor A2 (EPHA2), two receptor tyrosine kinases (RTKs) which regulate a number of key cellular functions, as host factors for HCV entry [103] . The results showed that the identified RTKs mediated HCV entry by regulating CD81claudin-1 coreceptor associations and viral glycoproteindependent membrane fusion, implying that inhibition .....
    Document: Using a functional RNAi kinase screen, recent study identified epidermal growth factor receptor (EGFR) and ephrin receptor A2 (EPHA2), two receptor tyrosine kinases (RTKs) which regulate a number of key cellular functions, as host factors for HCV entry [103] . The results showed that the identified RTKs mediated HCV entry by regulating CD81claudin-1 coreceptor associations and viral glycoproteindependent membrane fusion, implying that inhibition of RTK function may constitute a new approach for the prevention and treatment of HCV infection.

    Search related documents:
    Co phrase search for related documents
    • HCV infection and new approach: 1, 2, 3, 4, 5, 6
    • HCV infection treatment prevention and treatment prevention: 1
    • host factor and kinase screen: 1
    • host factor and new approach: 1
    • host factor and recent study: 1, 2, 3
    • host factor and treatment prevention: 1, 2
    • host factor and tyrosine kinase: 1
    • kinase screen and receptor tyrosine kinase: 1
    • kinase screen and tyrosine kinase: 1, 2, 3
    • new approach and recent study: 1, 2, 3, 4
    • new approach and receptor tyrosine kinase: 1
    • new approach and treatment prevention: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
    • new approach and tyrosine kinase: 1, 2, 3
    • recent study and treatment prevention: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
    • recent study and tyrosine kinase: 1, 2, 3
    • receptor tyrosine kinase and treatment prevention: 1
    • receptor tyrosine kinase and tyrosine kinase: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
    • RTKs receptor tyrosine kinase and tyrosine kinase: 1
    • treatment prevention and tyrosine kinase: 1, 2, 3