Selected article for: "CEACAM PSG locus and low density"
Author: Chang, Chia Lin; Semyonov, Jenia; Cheng, Po Jen; Huang, Shang Yu; Park, Jae Il; Tsai, Huai-Jen; Lin, Cheng-Yung; Grützner, Frank; Soong, Yung Kuei; Cai, James J.; Hsu, Sheau Yu Teddy
Title: Widespread Divergence of the CEACAM/PSG Genes in Vertebrates and Humans Suggests Sensitivity to Selection
  • Document date: 2013_4_16
    • ID: 1jogs44p_36
    Snippet: Analysis of structural variations based on earlier array studies using low-density probes showed the presence of various types of gain and/or loss of genomic fragment encompassing CEACAM/ PSG genes [47, 48, 49, 50] . These CNVs range from a few kb to as large as 0.8 Mb in a small fraction of individuals ( Fig. S4 in File S1). Consistently, recent data based on high-density probe comparative genome hybridization analysis and/or genome sequencing i.....
    Document: Analysis of structural variations based on earlier array studies using low-density probes showed the presence of various types of gain and/or loss of genomic fragment encompassing CEACAM/ PSG genes [47, 48, 49, 50] . These CNVs range from a few kb to as large as 0.8 Mb in a small fraction of individuals ( Fig. S4 in File S1). Consistently, recent data based on high-density probe comparative genome hybridization analysis and/or genome sequencing indicated that CNVs at the CEACAM/PSG locus are pervasive, and most of these CNVs are results of large segmental duplications (Fig. 5a) [51, 52, 53] .

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