Selected article for: "NMR structure and structure form"
Author: Staple, David W; Butcher, Samuel E
Title: Pseudoknots: RNA Structures with Diverse Functions
  • Document date: 2005_6_14
    • ID: 0brhn8oc_9
    Snippet: The nuclear magnetic resonance (NMR) structure of the mouse mammary tumor virus (MMTV) frameshift-inducing pseudoknot was the fi rst structure of a frameshift-inducing pseudoknot ( Figure 2D ) [6] . The MMTV pseudoknot forms a compact structure of two guanine/cytosine-rich A-form helices. The MMTV pseudoknot has a bend of approximately 60º between the two helices, caused by an unpaired adenine that intercalates between the helices and may act as.....
    Document: The nuclear magnetic resonance (NMR) structure of the mouse mammary tumor virus (MMTV) frameshift-inducing pseudoknot was the fi rst structure of a frameshift-inducing pseudoknot ( Figure 2D ) [6] . The MMTV pseudoknot forms a compact structure of two guanine/cytosine-rich A-form helices. The MMTV pseudoknot has a bend of approximately 60º between the two helices, caused by an unpaired adenine that intercalates between the helices and may act as a hinge. Subsequent structural and functional studies of several variants of the MMTV pseudoknot reveal that the intercalated nucleotide and the resulting bend between stems 1 and 2 are required for effi cient frameshifting [28] .

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