Author: Kuban-Jankowska, Alicja; Sahu, Kamlesh K; Niedzialkowski, Pawel; Gorska, Magdalena; Tuszynski, Jack A; Ossowski, Tadeusz; Wozniak, Michal
Title: Redox process is crucial for inhibitory properties of aurintricarboxylic acid against activity of YopH: virulence factor of Yersinia pestis Document date: 2015_7_22
ID: 1irvzt8v_21
Snippet: The analysis of cyclic voltammograms (CVs) in a wide potential range ( Figure 4B ) indicates electrochemical reduction of ATA in the presence of negative potentials ranging from −2.0 V to −2.5 V. The current signal obtained for ATA is very similar to the cyclic voltammograms observed for hydrogen peroxide. The value of the current obtained for ATA at a concentration of 4.9 · 10 -4 M measured in DMSO solution is comparable to the hydrogen per.....
Document: The analysis of cyclic voltammograms (CVs) in a wide potential range ( Figure 4B ) indicates electrochemical reduction of ATA in the presence of negative potentials ranging from −2.0 V to −2.5 V. The current signal obtained for ATA is very similar to the cyclic voltammograms observed for hydrogen peroxide. The value of the current obtained for ATA at a concentration of 4.9 · 10 -4 M measured in DMSO solution is comparable to the hydrogen peroxide at a concentration of 1.5 · 10 −3 M performed for potentials from 1.25 V to 2.5 V. This may indicate that the hydrogen peroxide could be present during the redox process of ATA.
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