Author: Zhai, Shao-Lun; Lu, Shou-Sheng; Wei, Wen-Kang; Lv, Dian-Hong; Wen, Xiao-Hui; Zhai, Qi; Chen, Qin-Ling; Sun, Yan-Wei; Xi, Yun
Title: Reservoirs of Porcine Circoviruses: A Mini Review Document date: 2019_9_19
ID: 1e8qah7d_1
Snippet: Porcine circoviruses (PCVs) are members of the Circovirus genus of the Circoviridae family. Currently, there are three species in the genus, PCV type 1 (PCV1), PCV type 2 (PCV2), and PCV type 3 (PCV3), respectively. In 1974, PCV1 was discovered as a contaminant in porcine kidney cell lines (1) . Subsequent studies have confirmed that PCV1 is apathogenic in pigs (2) . In late 1990s, a new porcine disease, called post-weaning multisystemic wasting .....
Document: Porcine circoviruses (PCVs) are members of the Circovirus genus of the Circoviridae family. Currently, there are three species in the genus, PCV type 1 (PCV1), PCV type 2 (PCV2), and PCV type 3 (PCV3), respectively. In 1974, PCV1 was discovered as a contaminant in porcine kidney cell lines (1) . Subsequent studies have confirmed that PCV1 is apathogenic in pigs (2) . In late 1990s, a new porcine disease, called post-weaning multisystemic wasting syndrome (PMWS), emerged in North America and Europe (3) (4) (5) (6) , and PCV2 was confirmed as the causal pathogen (7, 8) . PCV2 has a global distribution and diverse genotypes (9, 10) . In 2016, the third PCV, named PCV3, was discovered using high-throughput sequencing technology in U.S. swine herds suffering from porcine dermatitis and nephropathy syndrome (PDNS), reproductive failure and other syndromes (11, 12) . A recent study suggested that PCV3 fulfilled Koch's postulates and could cause PDNS in piglets (13) .
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