Selected article for: "chronic inflammation and cytokine production"
Author: Ahanchian, Hamid; Jones, Carmen M; Chen, Yueh-sheng; Sly, Peter D
Title: Respiratory viral infections in children with asthma: do they matter and can we prevent them?
  • Document date: 2012_9_13
    • ID: 0mnsm6s4_47
    Snippet: Macrolides possess anti-inflammatory and immunomodulatory properties extending beyond their antibacterial activity [162] . Indeed, they can attenuate pro-inflammatory cytokine production by bronchial epithelial cells, neutrophils and macrophages that may contribute to clinical improvement in many patients with chronic airway inflammation [163] [164] [165] . Azithromycin has anti-rhinoviral activity and can reduce HRV replication and release by in.....
    Document: Macrolides possess anti-inflammatory and immunomodulatory properties extending beyond their antibacterial activity [162] . Indeed, they can attenuate pro-inflammatory cytokine production by bronchial epithelial cells, neutrophils and macrophages that may contribute to clinical improvement in many patients with chronic airway inflammation [163] [164] [165] . Azithromycin has anti-rhinoviral activity and can reduce HRV replication and release by increasing interferon production from epithelial cells [42, 166, 167] . Macrolide antibiotics inhibit RSV infection in human airway epithelial cells [168] . A three weeks treatment with clarithromycin in RSV bronchiolitis had statistically significant effects on hospital length of stay and rate of readmission to the hospital within six months after discharge [169] . However, direct evidence of macrolides preventing respiratory viral infection in children is lacking.

    Search related documents:
    Co phrase search for related documents
    • airway inflammation and chronic airway inflammation: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • airway inflammation and clinical improvement: 1, 2, 3
    • airway inflammation and cytokine production: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14
    • airway inflammation and epithelial cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
    • airway inflammation and hospital length: 1, 2
    • airway inflammation and HRV replication: 1
    • airway inflammation and human airway: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
    • airway inflammation and human airway epithelial cell: 1, 2
    • airway inflammation and interferon production: 1, 2, 3, 4
    • airway inflammation and macrophage neutrophil: 1, 2
    • antibacterial activity and cytokine production: 1, 2
    • antibacterial activity and epithelial cell: 1, 2, 3
    • antibacterial activity and interferon production: 1
    • antibacterial activity and macrophage neutrophil: 1, 2
    • bronchial epithelial cell and cytokine production: 1
    • bronchial epithelial cell and epithelial cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • bronchial epithelial cell and human airway: 1, 2, 3, 4, 5, 6
    • bronchial epithelial cell and human airway epithelial cell: 1
    • bronchial epithelial cell and interferon production: 1, 2