Author: Atkins, John F.; Loughran, Gary; Bhatt, Pramod R.; Firth, Andrew E.; Baranov, Pavel V.
Title: Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use Document date: 2016_9_6
ID: 0s8huajd_31
Snippet: Coronaviruses, which have positive sense single-stranded RNA genomes, utilize high level −1 frameshifting for synthesis of their polymerase (103) (104) (105) . Study of infectious bronchitis viral sequences by Ian Brierley and his colleagues led to the discovery of one of the most important frameshift stimulatory elements (106) (107) (108) . Subsequent studies with both human coronavirus 229E (109) and SARS coronavirus (see below) revealed unex.....
Document: Coronaviruses, which have positive sense single-stranded RNA genomes, utilize high level −1 frameshifting for synthesis of their polymerase (103) (104) (105) . Study of infectious bronchitis viral sequences by Ian Brierley and his colleagues led to the discovery of one of the most important frameshift stimulatory elements (106) (107) (108) . Subsequent studies with both human coronavirus 229E (109) and SARS coronavirus (see below) revealed unexpected additional aspects.
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