Author: Atkins, John F.; Loughran, Gary; Bhatt, Pramod R.; Firth, Andrew E.; Baranov, Pavel V.
Title: Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use Document date: 2016_9_6
ID: 0s8huajd_81
Snippet: Antizyme 1 mRNA is present in high abundance, and its expression is regulated to yield low levels of protein which is unstable. There are two start codons with a mitochondrial localization signal encoded between the first and favored second start 34 codons downstream (292) . The frameshifting required for synthesis of functional antizyme occurs at the last codon of ORF1, and is +1......
Document: Antizyme 1 mRNA is present in high abundance, and its expression is regulated to yield low levels of protein which is unstable. There are two start codons with a mitochondrial localization signal encoded between the first and favored second start 34 codons downstream (292) . The frameshifting required for synthesis of functional antizyme occurs at the last codon of ORF1, and is +1.
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