Author: Makadiya, Niraj; Brownlie, Robert; van den Hurk, Jan; Berube, Nathalie; Allan, Brenda; Gerdts, Volker; Zakhartchouk, Alexander
Title: S1 domain of the porcine epidemic diarrhea virus spike protein as a vaccine antigen Document date: 2016_4_1
ID: 1r3doeic_20
Snippet: Piglets that regularly suckle the immune mother receive colostrum/milk antibody, a process that cofers passive immunity to the piglets. Therefore, we tested colostrum samples collected from the vaccinated and control sows on the day of farrowing for the presense of PEDV S1-specific IgA and IgG antibody titres. The IgA and IgG titers were higher in colostrum of the vaccinated sow compared to the control sow ( Fig. 5c and d) . The IgG titer levels .....
Document: Piglets that regularly suckle the immune mother receive colostrum/milk antibody, a process that cofers passive immunity to the piglets. Therefore, we tested colostrum samples collected from the vaccinated and control sows on the day of farrowing for the presense of PEDV S1-specific IgA and IgG antibody titres. The IgA and IgG titers were higher in colostrum of the vaccinated sow compared to the control sow ( Fig. 5c and d) . The IgG titer levels were 5-fold higher than IgA titer levels, but it is not surprising since IgG is the major isotype in sow colostrum whereas IgA predominates in milk [25] .
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