Author: Choe, Young June; Smit, Michael A.; Mermel, Leonard A.
Title: Seasonality of respiratory viruses and bacterial pathogens Document date: 2019_7_22
ID: 1a329gcy_17
Snippet: We previously reported peaks of MRSA infections during the summer and autumn seasons [5] . This seasonality may, in part, be associated with increased antibiotic prescriptions some months earlier, as previously reported [17] . The 7-month lag that we detected is longer than found in another study which detected a temporal relationship between fluoroquinolone prescriptions and ciprofloxacin-resistant MRSA after a 1-month lag period [18] . A recent.....
Document: We previously reported peaks of MRSA infections during the summer and autumn seasons [5] . This seasonality may, in part, be associated with increased antibiotic prescriptions some months earlier, as previously reported [17] . The 7-month lag that we detected is longer than found in another study which detected a temporal relationship between fluoroquinolone prescriptions and ciprofloxacin-resistant MRSA after a 1-month lag period [18] . A recent study revealed that antibiotics lacking MRSA activity, including fluoroquinolones, promote MRSA overgrowth in the nares and this may be related to finding increased MRSA detection in clinical isolates after exposure to such antibiotics [19] . Not surprisingly, a national antibiotic stewardship program has been associated with decreased MRSA prevalence [20] . We also found the circulation of respiratory viruses is likely associated with bacterial co-infection or superinfection due to S. pneumoniae (0-month lag with OR = 1.01) as previously reported [3] .
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