Author: Zhang, Chi; Xiu, Leshan; Xiao, Yan; Xie, Zhengde; Ren, Lili; Peng, Junping
Title: Simultaneous Detection of Key Bacterial Pathogens Related to Pneumonia and Meningitis Using Multiplex PCR Coupled With Mass Spectrometry Document date: 2018_4_5
ID: 0k2blp7n_1
Snippet: Pneumonia and meningitis continue to be an enormous public health burden. According to the Global Burden of Disease 2015 study, more than 3.1 million deaths due to pneumonia and meningitis were estimated to have occurred in 2015. The two diseases together accounted for more than 15% of deaths in children under 5 years of age. Bacteria, viruses, and fungi can all cause pneumonia and meningitis, but bacteria are the leading cause of serious disease.....
Document: Pneumonia and meningitis continue to be an enormous public health burden. According to the Global Burden of Disease 2015 study, more than 3.1 million deaths due to pneumonia and meningitis were estimated to have occurred in 2015. The two diseases together accounted for more than 15% of deaths in children under 5 years of age. Bacteria, viruses, and fungi can all cause pneumonia and meningitis, but bacteria are the leading cause of serious disease and deaths (GBD 2015 Mortality and Causes of Death Collaborators, 2016) . For bacterial pathogens, the selection of appropriate antibiotics forms the basis of sound clinical management. However, this complex etiology and overlapping clinical presentations make it challenging to identify the causative organism.
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