Author: Weishan Huang; Sabrina Solouki; Chavez Carter; Song-Guo Zheng; Avery August
Title: Beyond type 1 regulatory T cells: co-expression of LAG3 and CD49b in IL-10-producing T cell lineages Document date: 2018_6_30
ID: ivyp5cgz_14
Snippet: Co-expression of LAG3 and CD49b marks both IL-10-producing CD4 + and CD8 + T cells 189 LAG3 and CD49b co-expression was previously reported to be a cell surface signature for 190 both mouse and human IL-10-producing CD4 + T cells that lack the expression of Foxp3 (also 191 known as type 1 regulatory T cells, Tr1 cells) [15] . We and others have previously reported that both CD4 + and CD8 + T cells (Fig. 1A) . Surprisingly, the resultant IL-10-pro.....
Document: Co-expression of LAG3 and CD49b marks both IL-10-producing CD4 + and CD8 + T cells 189 LAG3 and CD49b co-expression was previously reported to be a cell surface signature for 190 both mouse and human IL-10-producing CD4 + T cells that lack the expression of Foxp3 (also 191 known as type 1 regulatory T cells, Tr1 cells) [15] . We and others have previously reported that both CD4 + and CD8 + T cells (Fig. 1A) . Surprisingly, the resultant IL-10-producing CD8 + T cells 197
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