Selected article for: "host immunity and present study"
Author: Qian, Wei; Wei, Xiaoqin; Guo, Kelei; Li, Yongtao; Lin, Xian; Zou, Zhong; Zhou, Hongbo; Jin, Meilin
Title: The C-Terminal Effector Domain of Non-Structural Protein 1 of Influenza A Virus Blocks IFN-ß Production by Targeting TNF Receptor-Associated Factor 3
  • Document date: 2017_7_3
    • ID: 00mqmpzw_40
    Snippet: In summary, the present study demonstrated that TRAF3 is a target of the C-terminal ED (AA126 to 225) of H5N1 NS1 protein, revealing a novel function of the NS1 protein in modulating host innate immunity and possibly facilitating IAV infection. The physiological significance of the NS1 ED in IAV replication and its pathological role in flu diseases warrant further investigation to probe the potential value of this molecule as a therapeutic and/or.....
    Document: In summary, the present study demonstrated that TRAF3 is a target of the C-terminal ED (AA126 to 225) of H5N1 NS1 protein, revealing a novel function of the NS1 protein in modulating host innate immunity and possibly facilitating IAV infection. The physiological significance of the NS1 ED in IAV replication and its pathological role in flu diseases warrant further investigation to probe the potential value of this molecule as a therapeutic and/or disease prevention target.

    Search related documents:
    Co phrase search for related documents
    • IAV infection and novel function: 1, 2
    • IAV replication and immunity innate: 1, 2
    • IAV replication and NS1 protein: 1, 2, 3, 4, 5
    • IAV replication and present study: 1, 2, 3, 4, 5, 6
    • immunity innate and novel function: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • immunity innate and NS1 protein: 1, 2, 3, 4, 5, 6, 7
    • immunity innate and pathological role: 1, 2, 3, 4
    • immunity innate and potential value: 1, 2, 3, 4, 5
    • immunity innate and present study: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58
    • investigation warrant and present study: 1, 2, 3, 4
    • molecule potential value and potential value: 1
    • novel function and NS1 protein: 1
    • novel function and NS1 protein novel function: 1
    • novel function and present study: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • NS1 protein and present study: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
    • pathological role and potential value: 1
    • pathological role and present study: 1, 2, 3, 4, 5, 6, 7, 8
    • physiological significance and present study: 1
    • potential value and present study: 1, 2, 3, 4, 5, 6, 7, 8