Selected article for: "innate immunity and present study"
Author: Qian, Wei; Wei, Xiaoqin; Guo, Kelei; Li, Yongtao; Lin, Xian; Zou, Zhong; Zhou, Hongbo; Jin, Meilin
Title: The C-Terminal Effector Domain of Non-Structural Protein 1 of Influenza A Virus Blocks IFN-ß Production by Targeting TNF Receptor-Associated Factor 3
  • Document date: 2017_7_3
    • ID: 00mqmpzw_40
    Snippet: In summary, the present study demonstrated that TRAF3 is a target of the C-terminal ED (AA126 to 225) of H5N1 NS1 protein, revealing a novel function of the NS1 protein in modulating host innate immunity and possibly facilitating IAV infection. The physiological significance of the NS1 ED in IAV replication and its pathological role in flu diseases warrant further investigation to probe the potential value of this molecule as a therapeutic and/or.....
    Document: In summary, the present study demonstrated that TRAF3 is a target of the C-terminal ED (AA126 to 225) of H5N1 NS1 protein, revealing a novel function of the NS1 protein in modulating host innate immunity and possibly facilitating IAV infection. The physiological significance of the NS1 ED in IAV replication and its pathological role in flu diseases warrant further investigation to probe the potential value of this molecule as a therapeutic and/or disease prevention target.

    Search related documents:
    Co phrase search for related documents
    • disease prevention and host modulate: 1
    • disease prevention and IAV infection: 1
    • disease prevention and immunity innate: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
    • disease prevention and investigation warrant: 1
    • disease prevention and NS1 protein: 1
    • disease prevention and potential value: 1, 2, 3, 4, 5
    • disease prevention and present study: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72
    • disease prevention and therapeutic disease prevention target: 1
    • disease prevention target and therapeutic disease prevention target: 1
    • flu disease and present study: 1, 2, 3, 4, 5, 6
    • host modulate and IAV replication: 1
    • host modulate and immunity innate: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
    • host modulate and present study: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
    • IAV infection and immunity innate: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • IAV infection and novel function: 1, 2
    • IAV infection and NS1 protein: 1, 2, 3, 4, 5
    • IAV infection and NS1 protein novel function: 1
    • IAV infection and present study: 1, 2, 3, 4, 5, 6, 7
    • IAV replication and immunity innate: 1, 2