Author: Antunes, Agostinho; Troyer, Jennifer L.; Roelke, Melody E.; Pecon-Slattery, Jill; Packer, Craig; Winterbach, Christiaan; Winterbach, Hanlie; Hemson, Graham; Frank, Laurence; Stander, Philip; Siefert, Ludwig; Driciru, Margaret; Funston, Paul J.; Alexander, Kathy A.; Prager, Katherine C.; Mills, Gus; Wildt, David; Bush, Mitch; O'Brien, Stephen J.; Johnson, Warren E.
Title: The Evolutionary Dynamics of the Lion Panthera leo Revealed by Host and Viral Population Genomics Document date: 2008_11_7
ID: 095u8eaj_15
Snippet: Not unexpectedly, FIV Ple pairwise genetic distances, represented as population F ST among the eight lion FIV-infected populations, were not significantly correlated with geographic distance (R 2 = 0.08; Mantel's test, P = 0.165) (Figure 3 ), and affirms that patterns of viral dissemination do not conform to a strict isolation-by-distance model. Rather, the two distinct clusters observed ( Figure 3 ) reflect the complex distribution of FIV Ple am.....
Document: Not unexpectedly, FIV Ple pairwise genetic distances, represented as population F ST among the eight lion FIV-infected populations, were not significantly correlated with geographic distance (R 2 = 0.08; Mantel's test, P = 0.165) (Figure 3 ), and affirms that patterns of viral dissemination do not conform to a strict isolation-by-distance model. Rather, the two distinct clusters observed ( Figure 3 ) reflect the complex distribution of FIV Ple among African lions. Indeed, despite the low geographic distance within East-African lion populations, the FIV Ple genetic divergence showed a broader range in F ST (0.03 to 0.79 for most of first cluster; Figure 3 ). By contrast, approximately half of the range in F ST (0.26 to 0.69 for the second cluster; Figure 3 ) was observed among East and Southern Africa in spite of its large geographic separation. In contrast with the patterns observed in lions, linearized F ST estimates [24] for FIV Ple were better correlated with log geographic distance (two-dimensional lattice model) (R 2 = 0.15) than with geographic distance (one-dimensional model) (R 2 = 0.02), although in both cases the Mantel's test was not significant (P.0.2474) ( Figure S2 ).
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