Author: Ross D. Overacker; Somdev Banerjee; George F. Neuhaus; Selena Milicevic Sephton; Alexander Herrmann; James A. Strother; Ruth Brack-Werner; Paul R. Blakemore; Sandra Loesgen
Title: Biological Evaluation of Molecules of the azaBINOL Class as Antiviral Agents: Specific Inhibition of HIV-1 RNase H Activity by 7-Isopropoxy-8-(naphth-1-yl)quinoline Document date: 2019_1_23
ID: m2zw8eq4_20
Snippet: RNase H activity of HIV RT with an IC50 of 14.2 µM, within the same range as the low 230 micromolar cell-based assay results ( inhibitors and therefore allow for a more favorable therapeutic window. 8, 9 249.....
Document: RNase H activity of HIV RT with an IC50 of 14.2 µM, within the same range as the low 230 micromolar cell-based assay results ( inhibitors and therefore allow for a more favorable therapeutic window. 8, 9 249
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