Author: Oude Munnink, Bas B; Canuti, Marta; Deijs, Martin; de Vries, Michel; Jebbink, Maarten F; Rebers, Sjoerd; Molenkamp, Richard; van Hemert, Formijn J; Chung, Kevin; Cotten, Matthew; Snijders, Fransje; Sol, Cees JA; van der Hoek, Lia
Title: Unexplained diarrhoea in HIV-1 infected individuals Document date: 2014_1_13
ID: 0e9l19kp_32
Snippet: Two variants of non-A non-B hepatitis virus (NANBH-1 and NANBH-2) were found. The NANBH virus has been described in the 1980's in patients with non A non B hepatitis, at a time that hepatitis C virus was not identified yet [45] . Since then no other study has investigated its presence in humans. NANBH viruses are circular dsDNA viruses and since the viruses were found by VIDISCA-454 in two patients with unexplained diarrhoea, their entire genome .....
Document: Two variants of non-A non-B hepatitis virus (NANBH-1 and NANBH-2) were found. The NANBH virus has been described in the 1980's in patients with non A non B hepatitis, at a time that hepatitis C virus was not identified yet [45] . Since then no other study has investigated its presence in humans. NANBH viruses are circular dsDNA viruses and since the viruses were found by VIDISCA-454 in two patients with unexplained diarrhoea, their entire genome was sequenced. The viral genomes consist of 5,005 (NANBH-1) and 5,687 (NANBH-2) bps and both contain 4 open reading frames. The NANBH-2 virus is similar to the NANBH-1 except for a 687 nucleotide insertion in a non-coding region.
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