Author: Wang, Ting; Yin, Huiquan; Li, Yan; Zhao, Lingxiao; Sun, Xiahui; Cong, Hua
Title: Vaccination with recombinant adenovirus expressing multi-stage antigens of Toxoplasma gondii by the mucosal route induces higher systemic cellular and local mucosal immune responses than with other vaccination routes Document date: 2017_4_3
ID: 1ay8y7li_1
Snippet: Toxoplasma gondii is a single-cell obligate intracellular protozoan with an infection rate of approximately 25%-30% in the worldwide population [6, 13, 29] . In pregnant women, this parasite may threaten health or even be fatal concerning congenitally infected fetuses [30] . It is also a major opportunistic infection in immunodeficient individuals, causing toxoplasmic encephalitis and retinochoroiditis [7, 17, 33] . As a result, an effective vacc.....
Document: Toxoplasma gondii is a single-cell obligate intracellular protozoan with an infection rate of approximately 25%-30% in the worldwide population [6, 13, 29] . In pregnant women, this parasite may threaten health or even be fatal concerning congenitally infected fetuses [30] . It is also a major opportunistic infection in immunodeficient individuals, causing toxoplasmic encephalitis and retinochoroiditis [7, 17, 33] . As a result, an effective vaccine against T. gondii is urgently needed to prevent this disease.
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