Author: Wang, Ting; Yin, Huiquan; Li, Yan; Zhao, Lingxiao; Sun, Xiahui; Cong, Hua
Title: Vaccination with recombinant adenovirus expressing multi-stage antigens of Toxoplasma gondii by the mucosal route induces higher systemic cellular and local mucosal immune responses than with other vaccination routes Document date: 2017_4_3
ID: 1ay8y7li_41
Snippet: response. It is known that production of IgG subtype is driven by cytokines secreted during cellular immune responses. Therefore, the presence of IgG1 and IgG2a indirectly suggests that the vaccination protocol also promoted activation of a cellmediated response [12, 31] . These data suggest that Ad-UMAS immunization by the mucosal vaccination route was capable of eliciting similar systemic humoral antibody responses compared with those elicited .....
Document: response. It is known that production of IgG subtype is driven by cytokines secreted during cellular immune responses. Therefore, the presence of IgG1 and IgG2a indirectly suggests that the vaccination protocol also promoted activation of a cellmediated response [12, 31] . These data suggest that Ad-UMAS immunization by the mucosal vaccination route was capable of eliciting similar systemic humoral antibody responses compared with those elicited by the intramuscular pathway in vaccinated mice.
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