Selected article for: "biological activity and structure activity"

Author: Ross D. Overacker; Somdev Banerjee; George F. Neuhaus; Selena Milicevic Sephton; Alexander Herrmann; James A. Strother; Ruth Brack-Werner; Paul R. Blakemore; Sandra Loesgen
Title: Biological Evaluation of Molecules of the azaBINOL Class as Antiviral Agents: Specific Inhibition of HIV-1 RNase H Activity by 7-Isopropoxy-8-(naphth-1-yl)quinoline
  • Document date: 2019_1_23
  • ID: m2zw8eq4_27
    Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. Future studies are planned to optimize the azaBINOL core structure to increase HIV-1 299 activity by improving HIV-1 binding, solubility, and to reduce cytotoxicity. It is anticipated that 300 the absolute configuration of the biaryl system will influence biological activity but to what 301.....
    Document: The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. Future studies are planned to optimize the azaBINOL core structure to increase HIV-1 299 activity by improving HIV-1 binding, solubility, and to reduce cytotoxicity. It is anticipated that 300 the absolute configuration of the biaryl system will influence biological activity but to what 301

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