Author: Penno, Christophe; Kumari, Romika; Baranov, Pavel V.; van Sinderen, Douwe; Atkins, John F.
Title: Stimulation of reverse transcriptase generated cDNAs with specific indels by template RNA structure: retrotransposon, dNTP balance, RT-reagent usage Document date: 2017_9_29
ID: k4gtl2o7_59
Snippet: Extrapolating from the polymerase properties identified here to other polymerases, the recent increase in the modest number of known occurrences of productive utilization of transcription slippage for enriching gene expression, seems set to further increase. More generally, it extends awareness of the potential for template structure to stimulate slippage by diverse types of polymerase, and permits further parallels between context features that .....
Document: Extrapolating from the polymerase properties identified here to other polymerases, the recent increase in the modest number of known occurrences of productive utilization of transcription slippage for enriching gene expression, seems set to further increase. More generally, it extends awareness of the potential for template structure to stimulate slippage by diverse types of polymerase, and permits further parallels between context features that promote ribosomal frameshifting and transcription slippage.
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