Author: Chung, James J.; Rayburn, Maire C.; Chigerwe, Munashe
Title: Randomized controlled clinical trial on the effect of oral immunoglobulin supplementation on neonatal dairy calves with diarrhea Document date: 2019_5_24
ID: k5k1eeev_15
Snippet: Time to resolution of diarrhea with 95% confidence intervals (CIs) as a function of group assignment was determined using survival analysis by construction of Kaplan-Meier plots. For the survival analysis, the entry point into the study was at enrollment, and the exit point was at 14 days after enrollment. The specified outcome of interest was resolution of diarrhea based on fecal scoring. At the exit time point, calves that did not have the outc.....
Document: Time to resolution of diarrhea with 95% confidence intervals (CIs) as a function of group assignment was determined using survival analysis by construction of Kaplan-Meier plots. For the survival analysis, the entry point into the study was at enrollment, and the exit point was at 14 days after enrollment. The specified outcome of interest was resolution of diarrhea based on fecal scoring. At the exit time point, calves that did not have the outcome of interest (resolution of diarrhea) were censored. Differences in time to resolution of diarrhea among the 3 survival plots were compared using the Sidak test. The effect of age at enrollment, serum IgG concentrations, fecal score at enrollment, medical treatments, and daily milk intake as explanatory variables for time to resolution of diarrhea was determined using the Cox proportional hazard model, and subsequent determination of risk ratios. Risk ratios <1 or >1 with a corresponding P < .05 were considered significant. In all analyses P <.05 was significant.
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