Global Influenza Hospital-based Surveillance Network (GIHSN): results of surveillance of influenza and other respiratory viruses in hospitalised patients in Brazil, 2015

Raboni, Sonia M; Moura, Fernanda EA; Caetano, Braulia C; Avanzi, Valéria M; Pereira, Luciane A; Nogueira, Meri B; Vidal, Luine R; Tavares, Isabel CF; Pradel, Florence K; Picot, Valentina S; Puig-Barbera, Joan; Siqueira, Marilda M

As shown in Table 2 , 9/37 influenza)positive cases fell in the severe spectrum, and severe disease was significantly more frequent in influenza)infected patients than in those with ORV (30% vs. 11%). In an adjusted analysis, only age was associated with this outcome ( = 0.01), whereas presence of comorbidities was not ( = 0.12). No difference in mortality was observed between influenza) and ORV)infected patients. Overall, the frequency of influenza viruses in the study specimens was 6.5% subtyped influenza A. [18] Since 2014, the Brazilian Ministry of Health included children up to 4 years of age in the group of individuals at risk of severe influenza and, thus, started vaccination of this subpopulation. Data from the National Immunization Program show coverage rates above 83% among young children and pregnant women, 89% in the elderly, and 95% in health workers. [13, 17] . In the present study, it was observed that proportionally there were a higher percentage of patients from Curitiba vaccinated among the 3 sites.