Author: Lam, Yun W.; Evans, Vanessa C.; Heesom, Kate J.; Lamond, Angus I.; Matthews, David A.
Title: Proteomics Analysis of the Nucleolus in Adenovirus-infected Cells Document date: 2009_10_7
ID: jgxbpy4j_39
Snippet: The enrichment of p87 PIKAP (also known as PIK3R6) is also interesting. This protein is a regulatory subunit of phosphoinositide 3-kinase â¥, which is part of the phosphoinositide 3-kinase signaling pathway. These pathways cover a very wide range of responses from cellular growth to cellular motility. However, activation of phosphoinositide 3-kinase ⥠is linked mainly to host-wide responses to injury or infection (64) . Indeed, it is clear tha.....
Document: The enrichment of p87 PIKAP (also known as PIK3R6) is also interesting. This protein is a regulatory subunit of phosphoinositide 3-kinase â¥, which is part of the phosphoinositide 3-kinase signaling pathway. These pathways cover a very wide range of responses from cellular growth to cellular motility. However, activation of phosphoinositide 3-kinase ⥠is linked mainly to host-wide responses to injury or infection (64) . Indeed, it is clear that adenovirus does directly modulate the phosphoinositide 3-kinase pathway (65) .
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