Author: Noh, Heeju; Shoemaker, Jason E; Gunawan, Rudiyanto
Title: Network perturbation analysis of gene transcriptional profiles reveals protein targets and mechanism of action of drugs and influenza A viral infection Document date: 2018_4_6
ID: j80hnhpb_38
Snippet: For influenza A virus study, we performed a gene set enrichment analysis (GSEA) of the protein target predictions from ProTINA, DeMAND and DE analysis for the KEGG biological pathways (42), using the R package GAGE (Generally Applicable Gene-set/pathway Enrichment analysis) with Kolmogorov-Smirnov tests (43) . In the case of ProTINA and DeMAND, target proteins with zero score were excluded from the GSEA......
Document: For influenza A virus study, we performed a gene set enrichment analysis (GSEA) of the protein target predictions from ProTINA, DeMAND and DE analysis for the KEGG biological pathways (42), using the R package GAGE (Generally Applicable Gene-set/pathway Enrichment analysis) with Kolmogorov-Smirnov tests (43) . In the case of ProTINA and DeMAND, target proteins with zero score were excluded from the GSEA.
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