Author: Berger, Angela K.; Danthi, Pranav
Title: Reovirus Activates a Caspase-Independent Cell Death Pathway Document date: 2013_5_14
ID: jleccqqx_2
Snippet: The importance of apoptosis to viral pathogenesis (6) (7) (8) (9) (10) (11) (12) (13) (14) (15) (16) has led to numerous studies to examine the molecular basis of proapoptotic signaling following infection with mammalian orthoreovirus, henceforth referred to as reovirus (17) . Following receptor-mediated endocytosis, reovirus particles disassemble in the endosome and viral cores are deposited into the cytosol via the function of the viral membran.....
Document: The importance of apoptosis to viral pathogenesis (6) (7) (8) (9) (10) (11) (12) (13) (14) (15) (16) has led to numerous studies to examine the molecular basis of proapoptotic signaling following infection with mammalian orthoreovirus, henceforth referred to as reovirus (17) . Following receptor-mediated endocytosis, reovirus particles disassemble in the endosome and viral cores are deposited into the cytosol via the function of the viral membrane-penetration protein (17, 18) .
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