Author: Domingo, Esteban
Title: Mechanisms of viral emergence Document date: 2010_2_5
ID: k6v4am7l_24
Snippet: The number of infectious particles shed by each infected individual is critical not only because the amount of virus that is shed affects the probability of encountering a susceptible host, but also because the larger the number of infectious particles the broader the spectrum of mutants that will reach the recipient host individuals (Fig. 2) . Viral population numbers can be largely amplified in immunocompromised individuals, that have been term.....
Document: The number of infectious particles shed by each infected individual is critical not only because the amount of virus that is shed affects the probability of encountering a susceptible host, but also because the larger the number of infectious particles the broader the spectrum of mutants that will reach the recipient host individuals (Fig. 2) . Viral population numbers can be largely amplified in immunocompromised individuals, that have been termed ''super-shedders'' or ''super-spreaders'', and constitute large reservoirs of variant viruses [27, 38, 65, 68, 72, 76] .
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