Selected article for: "antiviral therapy and PCR assay"
Author: Cobo, Fernando
Title: Application of Molecular Diagnostic Techniques for Viral Testing
  • Document date: 2012_11_30
    • ID: jiy4cp4n_94
    Snippet: PCR is a specific and sensitive assay for detecting adenovirus DNA from a wide variety of clinical specimens, but results must be always interpreted in the context of the clinical findings of adenovirus disease. Quantitative realtime PCR is being now used for the evaluation of adenovirus infections in immunocompromised patients [77] . Moreover, quantification of adenovirus DNA could be useful for assessing response to antiviral therapy [78] . Rea.....
    Document: PCR is a specific and sensitive assay for detecting adenovirus DNA from a wide variety of clinical specimens, but results must be always interpreted in the context of the clinical findings of adenovirus disease. Quantitative realtime PCR is being now used for the evaluation of adenovirus infections in immunocompromised patients [77] . Moreover, quantification of adenovirus DNA could be useful for assessing response to antiviral therapy [78] . Real-time PCR assays mainly are used to detect adenovirus type 4 (subgroup E) that can cause respiratory, ocular and other infections. The sensitivity of real time PCR against conventional PCR is greater for the detection of adenovirus DNA [79] .

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