Author: Bautista-Hernández, Luis Antonio; Gómez-Olivares, José Luis; Buentello-Volante, Beatriz; Bautista-de Lucio, Victor Manuel
Title: Fibroblasts: The Unknown Sentinels Eliciting Immune Responses Against Microorganisms Document date: 2017_8_19
ID: j4lfwdbh_39
Snippet: The growth factors granulocyte/macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) play roles in immune responses, survival, cancer pathogenesis, proliferation of macrophages, erythrocytes, eosinophils, megakaryocytes, and multipotent progenitors. The expression of GM-CSF is associated with infl ammatory diseases, such as rheumatoid arthritis and infl ammatory renal disease. GM-CSF induces proinfl ammat.....
Document: The growth factors granulocyte/macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) play roles in immune responses, survival, cancer pathogenesis, proliferation of macrophages, erythrocytes, eosinophils, megakaryocytes, and multipotent progenitors. The expression of GM-CSF is associated with infl ammatory diseases, such as rheumatoid arthritis and infl ammatory renal disease. GM-CSF induces proinfl ammatory cytokines in response to exposure to LPS in mice. The production of G-CSF is induced by TLRs and ligands such as LPS. The G-CSF induces the recruitment of neutrophils to sites of infl ammation [47, 48] .
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