Selected article for: "ACC score and cross covariance"
Author: Kaliamurthi, Satyavani; Selvaraj, Gurudeeban; Kaushik, Aman Chandra; Gu, Ke-Ren; Wei, Dong-Qing
Title: Designing of CD8(+) and CD8(+)-overlapped CD4(+) epitope vaccine by targeting late and early proteins of human papillomavirus
  • Document date: 2018_10_2
    • ID: j0runrkf_8
    Snippet: CD8 + and its overlapped CD4 + epitopes of HPV In total, sequences of 139 proteins were extracted which included E1 (11), E2 (12), E4 (04), E5 (03), E6 (27) , E7 (26) , L1 (32) , and L2 (24) . Alignment-independent VaxiJen 2.0 tool was employed to determine the antigenicity of the complete list of selected sequences. The protective antigenic score was calculated based on the auto cross-covariance (ACC), which is the transformation of protein sequ.....
    Document: CD8 + and its overlapped CD4 + epitopes of HPV In total, sequences of 139 proteins were extracted which included E1 (11), E2 (12), E4 (04), E5 (03), E6 (27) , E7 (26) , L1 (32) , and L2 (24) . Alignment-independent VaxiJen 2.0 tool was employed to determine the antigenicity of the complete list of selected sequences. The protective antigenic score was calculated based on the auto cross-covariance (ACC), which is the transformation of protein sequences into normal vectors with essential amino acid properties. 45 (1)

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