Selected article for: "CNS immune surveillance and immune surveillance"
Author: Brabb, Thea; von Dassow, Peter; Ordonez, Nadia; Schnabel, Bryan; Duke, Blythe; Goverman, Joan
Title: In Situ Tolerance within the Central Nervous System as a Mechanism for Preventing Autoimmunity
  • Document date: 2000_9_18
    • ID: kcygxo7h_2
    Snippet: CNS immune privilege is believed to be one of the main components in maintaining ignorance in MBP-specific T cells. Immune privilege is maintained within the CNS by the blood-brain barrier that limits CNS trafficking by leukocytes (6) (7) (8) . Previous studies have suggested that only activated T cells are able to cross the blood-brain barrier and perform immune surveillance of the CNS (7, 9, 10) ......
    Document: CNS immune privilege is believed to be one of the main components in maintaining ignorance in MBP-specific T cells. Immune privilege is maintained within the CNS by the blood-brain barrier that limits CNS trafficking by leukocytes (6) (7) (8) . Previous studies have suggested that only activated T cells are able to cross the blood-brain barrier and perform immune surveillance of the CNS (7, 9, 10) .

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