Author: Jain, K.K.
Title: Synthetic Biology and Personalized Medicine Document date: 2012_8_16
ID: jejgkcql_51
Snippet: Silenced developmental regulators of stem cells can be reactivated by a synthetic transcription factor that interacts with chromatin rather than DNA [28] . Potential applications of stem cells modified with synthetic biology include the following: (1) Drug screening for personalized therapies. (2) Engineering of stem cells, to achieve new functions not present in our body, and to introduce them back into the donor, e.g. cells involved in immune r.....
Document: Silenced developmental regulators of stem cells can be reactivated by a synthetic transcription factor that interacts with chromatin rather than DNA [28] . Potential applications of stem cells modified with synthetic biology include the following: (1) Drug screening for personalized therapies. (2) Engineering of stem cells, to achieve new functions not present in our body, and to introduce them back into the donor, e.g. cells involved in immune response can be programmed to recognize specific microorganisms and target them in a more efficient way than our own immune system can. (3) To maintain a population level of ⤠cells in diabetics using auto-regulated differentiation of embryonic stem cells that counter-balances the auto-immune attenuation. (4) Tissue engineering with specific desirable properties.
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