Selected article for: "adaptive innate immunity and cell cell"

Author: Casanova, Victor; Sousa, Filipa H; Stevens, Craig; Barlow, Peter G
Title: Antiviral therapeutic approaches for human rhinovirus infections
  • Document date: 2018_6_12
  • ID: kl7holv4_26
    Snippet: In addition to regulating the interferon response, Poly I:C is a powerful inducer of proinflammatory cytokines and chemokines and has been linked to maturation of DCs, NK cell cytotoxicity and virus-specific T-cell responses [122, 123] . This amplification of innate and adaptive immunity provides protection against a range of viruses, including influenza, Rift Valley fever virus, rabies virus, SARS-Co-BV and RSV [124, 125, 126, 127, 128] . Data f.....
    Document: In addition to regulating the interferon response, Poly I:C is a powerful inducer of proinflammatory cytokines and chemokines and has been linked to maturation of DCs, NK cell cytotoxicity and virus-specific T-cell responses [122, 123] . This amplification of innate and adaptive immunity provides protection against a range of viruses, including influenza, Rift Valley fever virus, rabies virus, SARS-Co-BV and RSV [124, 125, 126, 127, 128] . Data from our own laboratory has shown that pretreatment of bronchial epithelial cells with 10 μg/ml of Poly I:C substantially affects RV RV1B replication (Figure 1) .

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