Author: Chan, Renee W. Y.; Poon, Leo L. M.
Title: The Emergence of Human Coronavirus EMC: How Scared Should We Be? Document date: 2013_4_9
ID: kna8kca6_11
Snippet: In clinical and epidemiological settings, further development of serological tests for HCoV-EMC is urgently needed. So far, a few immunofluorescence assays specific for HCoV-EMC have been reported (14) . It is essential to have reliable serological tools to determine whether HCoV-EMC has been circulating widely in the general population in the affected areas. This would also help answer whether there is sustained transmission of this novel corona.....
Document: In clinical and epidemiological settings, further development of serological tests for HCoV-EMC is urgently needed. So far, a few immunofluorescence assays specific for HCoV-EMC have been reported (14) . It is essential to have reliable serological tools to determine whether HCoV-EMC has been circulating widely in the general population in the affected areas. This would also help answer whether there is sustained transmission of this novel coronavirus in humans. This key information can also help reveal the spectrum of disease severity caused by HCoV-EMC in humans. HCoV-EMC is in bold. Branches representing bat coronavirus sequences are in red. All sequences were retrieved from the Taxonomy Browser of NCBI (http://www.ncbi.nlm.nih.gov/Taxonomy /Browser/wwwtax.cgi?modeÏUndef&idÏ11118&lvlÏ3&keepÏ1&srchmode Ï1&unlock). The tree was generated by using the neighbor-joining method in MEGA5 (http://www.megasoftware.net/). Details of bat coronaviruses that are genetically related to HCoV-EMC are as shown.
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