Selected article for: "antiviral response and ifn response"

Author: Hendaus, Mohamed A; Jomha, Fatima A; Alhammadi, Ahmed H
Title: Virus-induced secondary bacterial infection: a concise review
  • Document date: 2015_8_24
  • ID: k7eo2c26_15
    Snippet: The human myxovirus resistance protein 1 (MxA) is an important intermediary of the IFN-induced antiviral response against a variety of viruses. MxA expression is firmly modified by type I and type III IFNs, which also requires signal transducer and activator of transcription 1 signaling. Additionally, MxA has many characteristics similar to the superfamily of large guanosine triphosphatases. 78 MxA analysis could be beneficial to differentiate be.....
    Document: The human myxovirus resistance protein 1 (MxA) is an important intermediary of the IFN-induced antiviral response against a variety of viruses. MxA expression is firmly modified by type I and type III IFNs, which also requires signal transducer and activator of transcription 1 signaling. Additionally, MxA has many characteristics similar to the superfamily of large guanosine triphosphatases. 78 MxA analysis could be beneficial to differentiate between bacterial and viral infections. Engelmann et al 79 conducted a prospective, multicenter cohort study in different pediatric emergency departments in France on the role of MxA in the diagnosis of viral infections.

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