Successful treatment of feline leishmaniosis using a combination of allopurinol and N-methyl-glucamine antimoniate

Basso, Maria Alexandra; Marques, Cátia; Santos, Marcos; Duarte, Ana; Pissarra, Hugo; Carreira, L Miguel; Gomes, Lídia; Valério-Bolas, Ana; Tavares, Luís; Santos-Gomes, Gabriela; Pereira da Fonseca, Isabel

The cat was not vaccinated, but had been regularly protected against ectoparasites with fipronil and imidacloprid. At first admission, mild fever (39.5ºC) and dermatological lesions on the head and limbs were the only abnormalities on physical examination. About 20-25 skin nodules measuring 2-10 mm in diameter were distributed on the outer pinnal surfaces ( Figure 1a ) and orbital regions (Figure 1b ). Most of them were observed on the pinnae, where they gathered with coalescing patterns. Differential diagnosis was pyodermatitis, allergic reaction, autoimmune disease, neoplastic disease or A complete blood count and biochemical profile were used to evaluate the clinical status of the cat before treatment, after treatment and at all follow-up examinations. Urinalysis and urinary protein: creatinine ratio were evaluated 6 months after treatment. Haematological and biochemical values were within the reference intervals. Serum protein electrophoresis showed an albumin: globulin ratio, but a slight hypergammaglobulinaemia was evident ( Table 1 ).