Author: Lulin Huang; Yi Shi; Bo Gong; Li Jiang; Xiaoqi Liu; Jialiang Yang; Juan Tang; Chunfang You; Qi Jiang; Bo Long; Tao Zeng; Mei Luo; Fanwei Zeng; Fanxin Zeng; Shuqiang Wang; Xingxiang Yang; Zhenglin Yang
Title: Blood single cell immune profiling reveals the interferon-MAPK pathway mediated adaptive immune response for COVID-19 Document date: 2020_3_17
ID: 2okcuviq_21
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.03.15.20033472 doi: medRxiv preprint immune response to these antigens was detected for NC 1 and NC 3; for the NC 2, two antigens were detected (HIV-1 and influenza A) (Fig. 3H) . For the patient with influenza A (patient 11), the antigen and autoimmune responses of the yellow fever virus were detected. For the patient with acute pharyngitis (pa.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.03.15.20033472 doi: medRxiv preprint immune response to these antigens was detected for NC 1 and NC 3; for the NC 2, two antigens were detected (HIV-1 and influenza A) (Fig. 3H) . For the patient with influenza A (patient 11), the antigen and autoimmune responses of the yellow fever virus were detected. For the patient with acute pharyngitis (patient 12), EBV, HIV-1, influenza A and yellow fever virus antigens were detected, but there was no autoimmune response. For the patient with cerebral infarction (patient 13), no known antigens were detected. These results indicate that humans might use known immune recognition (mainly known RNA viruses) to fight against SARS-CoV-2.
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