Atti del 52° Congresso Nazionale: Società Italiana di Igiene, Medicina Preventiva e Sanità Pubblica (SItI)

In Apulia, a total of 866 preterm infants out of 936 (92.5%) received the first dose of hexavalent vaccine and 57.6% were vaccinated by the 3rd month of age as recommended. Out of 866, 80.8% received the DTaP2-IPV-HB-Hib vaccine. We interviewed the parents of 339 preterm infants vaccinated with the DTaP2-IPV-HB-Hib vaccine, 97.8% of whom received co-administration with PCV13 and 72.5% also with anti-rotavirus. The most common local reactions were: pain ( Compared to the expected frequency of AEs in term-born infants, in our preterm population the injection site induration, nodule and the rash were more frequent, while loss of appetite, vomiting and persistent crying were less frequent.