Author: Magnusson, Jesper; Westin, Johan; Andersson, Lars-Magnus; Lindh, Magnus; Brittain-Long, Robin; Nordén, Rickard; Riise, Gerdt C.
Title: Viral Respiratory Tract Infection During the First Postoperative Year Is a Risk Factor for Chronic Rejection After Lung Transplantation Document date: 2018_7_11
ID: jtgcj91t_41
Snippet: In conclusion, this study suggests that VRTIs during the first postoperative year, in particular those caused by coronavirus, could be an important risk factor for long-term CLAD development. Using a systematic prospective recording of symptoms, we also found that a majority of these VRTIs were asymptomatic. Further mechanistic studies of viral interaction in transplanted lungs, and larger multicenter trials using standardized sampling and diagno.....
Document: In conclusion, this study suggests that VRTIs during the first postoperative year, in particular those caused by coronavirus, could be an important risk factor for long-term CLAD development. Using a systematic prospective recording of symptoms, we also found that a majority of these VRTIs were asymptomatic. Further mechanistic studies of viral interaction in transplanted lungs, and larger multicenter trials using standardized sampling and diagnostic methods, are warranted to better understand the effect of viral infections on long-term outcome after LTx.
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