Author: Noh, Heeju; Shoemaker, Jason E; Gunawan, Rudiyanto
Title: Network perturbation analysis of gene transcriptional profiles reveals protein targets and mechanism of action of drugs and influenza A viral infection Document date: 2018_4_6
ID: j80hnhpb_26
Snippet: Protein target scoring. In ProTINA, each candidate protein target is assigned a score based on the deviation of the expression of its downstream genes. More specifically, we computed the residuals of the linear regression problem in Equation (6) for each gene k, i.e......
Document: Protein target scoring. In ProTINA, each candidate protein target is assigned a score based on the deviation of the expression of its downstream genes. More specifically, we computed the residuals of the linear regression problem in Equation (6) for each gene k, i.e.
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