Author: Peri, Sateesh; Kulkarni, Asmita; Feyertag, Felix; Berninsone, Patricia M; Alvarez-Ponce, David
Title: Phylogenetic Distribution of CMP-Neu5Ac Hydroxylase (CMAH), the Enzyme Synthetizing the Proinflammatory Human Xenoantigen Neu5Gc Document date: 2017_12_30
ID: k596omcy_21
Snippet: The Xenopus tropicalis and Xenopus laevis CMAH sequences are annotated as pseudogenes in the NCBI RefSeq database. We aligned the two CDSs and estimated the nonsynonymous to synonymous divergence ratio, d N /d S , using the codeml progam of the PAML package, version 4.4 (Yang 2007) . We tested whether this d N /d S ratio was significantly different from 1 using a likelihood ratio test. Twice the difference of the loglikelihoods of both models (M0.....
Document: The Xenopus tropicalis and Xenopus laevis CMAH sequences are annotated as pseudogenes in the NCBI RefSeq database. We aligned the two CDSs and estimated the nonsynonymous to synonymous divergence ratio, d N /d S , using the codeml progam of the PAML package, version 4.4 (Yang 2007) . We tested whether this d N /d S ratio was significantly different from 1 using a likelihood ratio test. Twice the difference of the loglikelihoods of both models (M0 with a free d N /d S ratio vs. M0 with a fixed d N /d S of 1) was assumed to follow a v 2 distribution with one degree of freedom.
Search related documents:
Co phrase search for related documents- divergence ratio and NCBI RefSeq database: 1
- divergence ratio and synonymous divergence ratio: 1, 2
- freedom degree and PAML package: 1
- likelihood ratio test and ratio test: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76
- NCBI RefSeq database and synonymous divergence ratio: 1
Co phrase search for related documents, hyperlinks ordered by date